10.37 Chemical and Biological Reaction Engineering

Spring 2007

A real mixed tank can have bypasses, dead volumes, and recirculation.
In a real mixed tank, there is not perfect mixing due to dead volumes, bypasses, and recirculation. In a real plug flow reactor or packed bed reactor, there is back-mixing, axial dispersion, and channeling. See Lec #10 for how to model these behaviors. (Figure by MIT OCW.)

Course Description

This course applies the concepts of reaction rate, stoichiometry and equilibrium to the analysis of chemical and biological reacting systems, derivation of rate expressions from reaction mechanisms and equilibrium or steady state assumptions, design of chemical and biochemical reactors via synthesis of chemical kinetics, transport phenomena, and mass and energy balances. Topics covered include: chemical/biochemical pathways; enzymatic, pathway, and cell growth kinetics; batch, plug flow and well-stirred reactors for chemical reactions and cultivations of microorganisms and mammalian cells; heterogeneous and enzymatic catalysis; heat and mass transport in reactors, including diffusion to and within catalyst particles and cells or immobilized enzymes.

Recommended Citation

For any use or distribution of these materials, please cite as follows:

William Green, Jr., and K. Dane Wittrup, course materials for 10.37 Chemical and Biological Reaction Engineering, Spring 2007. MIT OpenCourseWare (http://ocw.mit.edu), Massachusetts Institute of Technology. Downloaded on [DD Month YYYY].

Technical Requirements

Special software is required to use some of the files in this course: .fig, .m, and .zip.

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Prof. William Green, Jr.
Prof. K. Dane Wittrup

Course Meeting Times

Two sessions / week
1 hour / week

One session / week
1 hour / week