20.410J / 2.798J / 6.524J / 10.537 Molecular, Cellular and Tissue Biomechanics (BE.410J)

Spring 2003

Diagram of cell migration, showing motion of actin away from leading edge.
Cellular motion is governed by the behavior of proteins like actin. (Image courtesy of OCW.)

Course Highlights

This course features an extensive set of lecture materials, including both slides and companion notes.

Course Description

This course develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena over a range of length scales. Topics include: structure of tissues and the molecular basis for macroscopic properties; chemical and electrical effects on mechanical behavior; cell mechanics, motility and adhesion; biomembranes; biomolecular mechanics and molecular motors. Experimental methods for probing structures at the tissue, cellular, and molecular levels will also be investigated.

This course was originally co-developed by Professors Alan Grodzinsky, Roger Kamm, and L. Mahadevan.

Donate Now


Prof. Roger Kamm
Prof. Patrick Doyle
Maxine Jonas

Course Meeting Times

Two sessions / week
1.5 hours / session